Yes.
There are limitations on the INST block. A guitar/bass that is connected to the GUITAR INPUT jack can use only normal patches. If a GK patch is selected, the INST block (synth sound) does not produce sound.
* "DYNAMIC SYNTH" is the only INST TYPE that can be selected for a normal patch. DYNAMIC SYNTH sounds differ between normal patches and GK patches.
* There are no limitations on the EFFECT block.